Astros vs Angels MLB Preview, Odds & Pitching: June 21, 2025

Saturday, June 21st, 2025

Previewing the matchup between the Houston Astros and the Los Angeles Angels set for Saturday, June 21, 2025, at Angel Stadium in Anaheim, California. The game is scheduled to begin at 9:38 PM EDT.

Game Details

The Houston Astros hold a season record of 44-32, placing them first in the AL West division. They have a road record of 17-19.

The Los Angeles Angels have a record of 36-39 overall and are fourth in the AL West. Their home record stands at 15-17.

Pitching Matchup

Houston Astros Probable Starter

Brandon Walter (0-0, 1.53 ERA, 0.91 WHIP, 19 strikeouts)

Los Angeles Angels Probable Starter

Jose Soriano (4-5, 3.54 ERA, 1.46 WHIP, 70 strikeouts)

Betting Odds

Astros: -119

Angels: -100

Over/Under: 8 1/2 runs

Series Outlook

This is the fifth meeting between these two teams this season. The Houston Astros currently lead the season series against the Los Angeles Angels with a 3-1 record.

The Astros won the previous game in the current series.

Team Performance Highlights

Los Angeles Angels

The Angels rank fourth in Major League Baseball with 107 total home runs this season.

Houston Astros

The Astros have an impressive 21-4 record in games where they have not allowed a home run.

Top Performers

Los Angeles Angels

Zach Neto has contributed 13 doubles, a triple, and 10 home runs for the Angels.

Jo Adell has been hot recently, going 7 for 35 with four home runs over the last 10 games.

Houston Astros

Isaac Paredes leads the Astros with 10 doubles, a triple, 16 home runs, and 45 RBI while maintaining a .253 batting average.

Jeremy Pena is also in good form, recording 16 hits in 42 at-bats over his last 10 games, including two doubles and a home run.

Recent Form

Los Angeles Angels (Last 10 Games)

Record: 5-5

Batting Average: .209

ERA: 3.30

Run Differential: Outscored by nine runs

Houston Astros (Last 10 Games)

Record: 8-2

Batting Average: .301

ERA: 2.57

Run Differential: Outscored opponents by 32 runs

Injury Report

Los Angeles Angels Injuries

Jorge Soler: 10-Day IL (back)

Chris Taylor: 10-Day IL (hand)

Yoan Moncada: 10-Day IL (knee)

Robert Stephenson: 15-Day IL (biceps)

Ben Joyce: 60-Day IL (shoulder)

Anthony Rendon: 60-Day IL (hip)

Houston Astros Injuries

Brendan Rodgers: 10-Day IL (oblique)

Lance McCullers: 15-Day IL (foot)

Jacob Melton: 10-Day IL (ankle)

Spencer Arrighetti: 60-Day IL (thumb)

Chas McCormick: 10-Day IL (oblique)

Ronel Blanco: 60-Day IL (elbow)

Zach Dezenzo: 10-Day IL (hand)

Hayden Wesneski: 60-Day IL (elbow)

Yordan Alvarez: 10-Day IL (hand)

Luis Garcia: 60-Day IL (elbow)

Cristian Javier: 60-Day IL (elbow)

J.P. France: 60-Day IL (shoulder)

Taylor Trammell: 10-Day IL (calf)

Pedro Leon: 10-Day IL (knee)

In summary

The Houston Astros (44-32) visit the Los Angeles Angels (36-39) on June 21, 2025, for their fifth meeting of the season, with the Astros leading the series 3-1. Houston, first in the AL West, sends Brandon Walter (0-0, 1.53 ERA) to the mound against Los Angeles' Jose Soriano (4-5, 3.54 ERA). Betting odds favor the Astros (-119) with an over/under of 8.5 runs. Key performers include Isaac Paredes for the Astros and Zach Neto for the Angels. The Astros are in better recent form (8-2) compared to the Angels (5-5). Both teams are dealing with multiple injuries. The game is scheduled for 9:38 PM EDT in Anaheim.

Related Links

• Houston Astros News & Updates
• Houston Astros Schedule & Scores
• Los Angeles Angels News & Updates
• Los Angeles Angels Schedule & Scores
• MLB News