Boston Red Sox at San Francisco Giants Game Preview - June 22, 2025

Sunday, June 22nd, 2025

The San Francisco Giants (43-34, second in the NL West) and the Boston Red Sox (40-38, fourth in the AL East) face off on Sunday, June 22, 2025, in San Francisco. The three-game series is currently tied 1-1.

The game is scheduled for 4:05 p.m. EDT.

The odds for the game have the Giants favored at -159, while the Red Sox are +133. The over/under for total runs scored is 7 1/2.

Pitching Matchup

Red Sox: Lucas Giolito (3-1, 4.73 ERA, 1.42 WHIP, 41 strikeouts)

Giants: Robbie Ray (8-2, 2.68 ERA, 1.12 WHIP, 97 strikeouts)

Team Notes

San Francisco Giants

San Francisco boasts a strong 24-14 record at home. Overall, they stand at 43-34. The Giants pitching staff has been a key factor in their success, holding the second-ranked team ERA in the NL at 3.28.

Boston Red Sox

Boston holds a 40-38 overall record, with an 18-21 mark when playing on the road. Close games have been a challenge for the Red Sox, who have a 9-18 record in contests decided by a single run.

Key Players

For the Giants, Rafael Devers has been a major offensive threat, recording 19 doubles and 16 home runs. Mike Yastrzemski is in good recent form, hitting 13 for 34 with three doubles and five RBI over the last 10 games.

For the Red Sox, Ceddanne Rafaela has contributed with 12 doubles, two triples, seven home runs, and 28 RBI. Marcelo Mayer has shown power recently, hitting three home runs in his last 10 games, despite a 4 for 29 batting average in that span.

Recent Performance

Giants: The Giants are 4-6 in their last 10 games, posting a .242 batting average and a 4.54 ERA. They have been outscored by four runs in this stretch.

Red Sox: The Red Sox are hot, going 8-2 in their last 10 games. They have a low .196 batting average in this period but a dominant 2.12 ERA, outscoring their opponents by four runs.

Injury Report

Giants Injuries

Jerar Encarnacion: 10-Day IL (oblique)

Matt Chapman: 10-Day IL (hand)

Tom Murphy: 60-Day IL (back)

Red Sox Injuries

Jordan Hicks: 15-Day IL (toe)

Josh Winckowski: 60-Day IL (elbow)

Nick Burdi: 15-Day IL (knee)

Justin Slaten: 15-Day IL (shoulder)

Liam Hendriks: 15-Day IL (hip)

Alex Bregman: 10-Day IL (quadricep)

Triston Casas: 60-Day IL (knee)

Masataka Yoshida: 60-Day IL (shoulder)

Kutter Crawford: 60-Day IL (knee)

Tanner Houck: 15-Day IL (flexor)

Chris Murphy: 60-Day IL (elbow)

Patrick Sandoval: 60-Day IL (elbow)

In summary

The San Francisco Giants host the Boston Red Sox on Sunday, June 22, 2025, in the rubber match of their three-game series. The series is tied 1-1. The Giants, with a 43-34 record and a strong home stand (24-14), send Robbie Ray (8-2, 2.68 ERA) to the mound. The Red Sox, holding a 40-38 record, counter with Lucas Giolito (3-1, 4.73 ERA). Key players include Rafael Devers and Mike Yastrzemski for the Giants, and Ceddanne Rafaela and Marcelo Mayer for the Red Sox. Boston is in better recent form (8-2) compared to San Francisco (4-6), despite struggling with one-run games (9-18). The Giants have a notable advantage in team ERA (3.28). Both teams have several players on the injured list.

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