Boston Red Sox vs. Baltimore Orioles: Game Preview, Odds, and Key Players for August 27, 2025 Matchup

Wednesday, August 27th, 2025

Boston Red Sox vs. Baltimore Orioles: MLB Matchup Preview

The Boston Red Sox (73-60), holding second place in the AL East, visit the Baltimore Orioles (60-72), currently fifth in the division, for a key matchup at Oriole Park at Camden Yards on Wednesday at 6:35 p.m. ET. Boston enters the game with a 2-0 series lead and a slight edge in the season series, leading 6-5 over Baltimore.

Pitching Matchup

The Red Sox are expected to start Brayan Bello (10-6, 3.07 ERA, 1.22 WHIP, 102 strikeouts), while the Orioles counter with Dietrich Enns (1-2, 4.97 ERA, 1.52 WHIP, 32 strikeouts). Boston opens as the favorite at -157, with the Orioles at +132. The over/under is set at 9 runs.

Team Performance and Season Series

Baltimore has a 31-35 record at home and is 38-14 in games where they score five or more runs. Boston owns a 32-35 roadmap but shines when their offense is clicking, boasting a 47-12 record when scoring at least five runs. This is the 12th meeting between the clubs this season, with Boston up 6-5 in head-to-head matchups.

Standout Players

For the Orioles, Gunnar Henderson leads the way with a .281 batting average, adding 30 doubles, five triples, and 16 home runs. Jeremiah Jackson has contributed significantly in recent games, going 15-for-41 with a home run and six RBIs across the last 10 contests.

Recent Form

Over their last 10 games, the Orioles have gone 4-6, posting a .247 team batting average and a 4.11 ERA, narrowly outscoring opponents. In contrast, the Red Sox are 6-4 in their past 10, batting .245 with a strong 3.26 ERA and outpacing their opposition by 12 runs overall.

Injury Report

Orioles: Scott Blewett (elbow), Gary Sanchez (knee), Jordan Westburg (ankle), Felix Bautista (shoulder), Brandon Young (hamstring), Adley Rutschman (oblique), Zach Eflin (back), Tyler O'Neill (wrist), Colin Selby (hamstring), Jorge Mateo (elbow), Cody Poteet (shoulder), Grayson Rodriguez (elbow), Albert Suarez (shoulder), Tyler Wells (elbow) are all sidelined with injuries.

Red Sox: Richard Fitts (biceps), Wilyer Abreu (calf), Rob Refsnyder (oblique), Luis Guerrero (elbow), Tanner Houck (flexor), Hunter Dobbins (ACL), Marcelo Mayer (wrist), Liam Hendriks (hip), Justin Slaten (shoulder), Josh Winckowski (elbow), Triston Casas (knee), Kutter Crawford (knee), Patrick Sandoval (elbow) are on the injured list.

Weather

Today at Oriole Park at Camden Yards, expect warm conditions with temperatures in the mid-80s, mostly clear skies, and a slight breeze around 8 mph. There is little chance of precipitation, making for ideal baseball weather with no anticipated disruptions to the game.

In summary

The Boston Red Sox seek to extend their series advantage against the Baltimore Orioles in game 12 of their season rivalry. Strong pitching from Brayan Bello and timely hitting will be key for the Red Sox, while the Orioles will look to capitalize on home field and offensive production from Gunnar Henderson and Jeremiah Jackson. With favorable weather and both teams eager for a divisional win, this matchup promises an exciting contest as the regular season winds down.

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