Boston Red Sox vs. Toronto Blue Jays: Game Preview, Odds, Pitching Matchup & Prediction – September 25, 2025

Thursday, September 25th, 2025

Boston Red Sox Take on Toronto Blue Jays in Series Finale

The Boston Red Sox (87-71, third in the AL East) face off against the Toronto Blue Jays (90-68, second in the AL East) in the concluding matchup of a three-game series. The Red Sox have the chance to complete a series sweep with another victory in Toronto.

Game Overview

The game is set to take place in Toronto at 7:07 p.m. EDT. The Blue Jays currently boast a strong 50-27 record at home and have secured a 90-68 overall mark this season. Notably, Toronto has gone 36-17 in games where they have not allowed a home run, highlighting their pitching strength.

Boston enters this contest with an 87-71 record overall, and a 41-39 mark on the road. The Red Sox’s offense ranks among the best in Major League Baseball, holding the fourth-best team batting average at .255.

This matchup marks the 13th meeting between the Blue Jays and Red Sox this season. Toronto leads the season series 7-5, adding to the significance of this final game between these division rivals.

Pitching Probables

The Red Sox will give the ball to Brayan Bello (11-8, 3.34 ERA, 1.24 WHIP, 121 strikeouts), while the Blue Jays are set to start Louie Varland (4-3, 3.10 ERA, 1.22 WHIP, 70 strikeouts). Oddsmakers have the Blue Jays favored at -138, while the Red Sox are set at +118. The over/under for the game is 8 runs.

Top Performers

For Boston, Jarren Duran has been a standout with 39 doubles, 13 triples, 16 home runs, and 82 RBIs. Alex Bregman has contributed as well, collecting two home runs and five RBIs in his last 10 games.

Recent Form

In their last 10 games, the Blue Jays have struggled, posting a 4-6 record with a .196 team batting average and a 5.32 ERA, having been outscored by 20 runs. Meanwhile, the Red Sox are 6-4 over their last 10 outings, recording a .281 batting average, a 3.60 ERA, and have outscored their opponents by 10 runs.

Injury Report

Blue Jays: Ty France (10-Day IL, oblique), Chris Bassitt (15-Day IL, back), Bo Bichette (10-Day IL, knee), Robinson Pina (60-Day IL, elbow), Nick Sandlin (60-Day IL, elbow), Yimi Garcia (60-Day IL, ankle), Bowden Francis (60-Day IL, shoulder), Ryan Burr (60-Day IL, shoulder), Angel Bastardo (60-Day IL, elbow).

Red Sox: Brennan Bernardino (15-Day IL, lat), Vaughn Grissom (60-Day IL, foot), Dustin May (15-Day IL, elbow), Jordan Hicks (15-Day IL, shoulder), Roman Anthony (10-Day IL, oblique), Hunter Dobbins (60-Day IL, ACL), Marcelo Mayer (60-Day IL, wrist), Richard Fitts (15-Day IL, biceps), Luis Guerrero (60-Day IL, elbow), Tanner Houck (60-Day IL, flexor), Liam Hendriks (60-Day IL, hip), Josh Winckowski (60-Day IL, elbow), Triston Casas (60-Day IL, knee), Kutter Crawford (60-Day IL, knee), Patrick Sandoval (60-Day IL, elbow).

In summary

The Red Sox vs. Blue Jays series finale in Toronto is a pivotal game in the AL East as these teams approach the season's end. Boston looks to sweep the series and close the season series gap, while Toronto aims to utilize its home field advantage and rebound from recent struggles. With strong pitching matchups and playoff positions on the line, this game is must-watch baseball for fans and an important contest for division standings.

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