New York Yankees vs. Baltimore Orioles Prediction, Odds & Preview – MLB Game on September 18, 2025

Thursday, September 18th, 2025

New York Yankees vs. Baltimore Orioles: Game Preview and Key Insights

The New York Yankees (85-67, second in the AL East) travel to face the Baltimore Orioles (72-80, fifth in the AL East) for an exciting Thursday night matchup at Oriole Park at Camden Yards.

Pitching Probables

The Yankees will send Max Fried (17-5, 3.03 ERA, 1.13 WHIP, 169 strikeouts) to the mound, while the Orioles will counter with Cade Povich (3-7, 5.05 ERA, 1.45 WHIP, 109 strikeouts). The betting odds favor the Yankees at -196, with the Orioles at +161 and the over/under set at nine runs.

Game Breakdown

The Orioles are aiming to extend their three-game home winning streak. They currently hold a 36-38 record at home and maintain a .307 on-base percentage, ranking 10th in the American League. The Yankees, with a 41-36 road record, boast the AL's top slugging percentage at .455.

This contest marks the seventh meeting between the two teams this season, with the season series tied 3-3.

Top Performers

For Baltimore, Jackson Holliday stands out with 21 doubles, three triples, 17 home runs, and 55 RBI, hitting .250 on the season. Gunnar Henderson has gone 10 for 38 with two doubles in his last 10 games.

For the Yankees, Aaron Judge leads with 29 doubles, two triples, and 48 home runs. Cody Bellinger has hit 11 for 40 with two doubles and two home runs over the last 10 games.

Recent Performance

In their last 10 games, the Orioles are 6-4 with a .218 batting average and a 3.69 team ERA, being outscored by nine runs. The Yankees are also 6-4 with a .255 batting average, but their pitching staff has struggled with a 5.93 ERA, and they've been outscored by 11 runs over that stretch.

Injury Report

Orioles: Albert Suarez (elbow), Shawn Dubin (elbow), Trevor Rogers (toe, day-to-day), Brandon Young (hamstring), Scott Blewett (elbow), Gary Sanchez (knee), Felix Bautista (shoulder), Adley Rutschman (oblique), Zach Eflin (back), Colin Selby (hamstring), Grayson Rodriguez (elbow).

Yankees: Brent Headrick (forearm), Jonathan Loaisiga (back), Clarke Schmidt (forearm), Oswaldo Cabrera (ankle), Jake Cousins (elbow), Gerrit Cole (elbow).

Weather

Today at Oriole Park at Camden Yards, expect comfortable baseball weather with temperatures around 76°F under mostly sunny skies. There's little chance of precipitation, making rain delays unlikely. Winds are light from the southwest at 6 mph, so any wind effect on play should be minimal—look for excellent conditions for both pitchers and hitters.

In summary

The Yankees and Orioles clash in a pivotal late-season matchup with both teams seeking to gain the upper hand in their season series. The pitching duel between Max Fried and Cade Povich, star players like Aaron Judge and Jackson Holliday, and favorable weather conditions all set the stage for an exciting contest in Baltimore. Stay tuned as both teams look to improve their standings in the AL East.

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