San Diego Padres at Miami Marlins: July 22, 2025 MLB Game Preview

Tuesday, July 22nd, 2025

The San Diego Padres (55-45, second in the NL West) are set to face the Miami Marlins (46-53, third in the NL East) in an MLB game on Tuesday, July 22, 2025, in Miami. First pitch is scheduled for 6:40 p.m. EDT.

Key Matchup Details

Pitching Matchup

For the Padres, Stephen Kolek (0-0) is slated to start. The Marlins will send Edward Cabrera (3-4) to the mound. Cabrera currently holds a 3.61 ERA, a 1.26 WHIP, and has recorded 86 strikeouts this season.

Betting Outlook

The Miami Marlins are favored at -112, while the San Diego Padres are close behind at -107. The over/under for total runs in the game is set at 8.

Series Context

This game marks the fifth meeting between these two teams this season. The San Diego Padres currently hold a 3-1 advantage in the season series and lead the current series 1-0.

Team Performance Insights

Home and Away Records

The Miami Marlins have a 22-29 record when playing at home, contributing to their overall record of 46-53. Notably, the Marlins have a strong 37-19 record in games where they accumulate at least eight hits.

The San Diego Padres enter this contest with a 24-27 record in road games and an overall season record of 55-45. The Padres rank 10th in the National League for team on-base percentage, holding a .316 OBP.

Top Players to Watch

Miami Marlins Key Hitters

Kyle Stowers has been a significant contributor for the Marlins, boasting 22 home runs, 36 walks, and 60 RBI, while maintaining an impressive .295 batting average. Xavier Edwards has also been hot recently, going 14 for 42 with five doubles, a triple, a home run, and seven RBI over his last 10 games.

San Diego Padres Key Hitters

Manny Machado leads the Padres offense with 23 doubles and 18 home runs. Xander Bogaerts has been productive over the last 10 games, hitting 13 for 34 with three doubles and a home run.

Recent Form

Marlins' Last 10 Games

The Marlins have a 5-5 record in their last 10 outings. During this span, they have a .257 batting average and a 3.48 ERA, outscoring their opponents by 11 runs.

Padres' Last 10 Games

The Padres come into this game with a strong 7-3 record over their last 10 games. They've posted a .248 batting average and an excellent 2.63 ERA, outscoring opponents by nine runs.

Injury Report

Miami Marlins Injuries

The Marlins' injury list includes Edward Cabrera (day-to-day, elbow), Jesus Tinoco (60-Day IL, forearm), Connor Norby (10-Day IL, wrist), Max Meyer (60-Day IL, hip), Ryan Weathers (60-Day IL, lat), Griffin Conine (60-Day IL, arm), Andrew Nardi (60-Day IL, back), and Braxton Garrett (60-Day IL, elbow).

San Diego Padres Injuries

The Padres are dealing with injuries to Michael King (60-Day IL, shoulder), Jhony Brito (60-Day IL, forearm), and Joe Musgrove (60-Day IL, elbow).

In summary

The San Diego Padres (55-45) will visit the Miami Marlins (46-53) on Tuesday, July 22, 2025, at 6:40 p.m. EDT. The Padres, currently second in the NL West, hold a 3-1 season series lead against the Marlins, who are third in the NL East. San Diego will send Stephen Kolek to the mound, while Miami counters with Edward Cabrera (3-4, 3.61 ERA). The Padres are favored at -107, with the Marlins at -112, and an over/under of 8 runs. Key players to watch include Miami's Kyle Stowers (.295 AVG, 22 HR) and San Diego's Manny Machado (18 HR). Both teams have been performing well recently, with the Padres at 7-3 and the Marlins at 5-5 in their last ten games, though both teams are managing significant injury lists.

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