San Diego Padres at San Francisco Giants - June 4, 2025 Preview

Wednesday, June 4th, 2025

San Diego Padres News & Updates

The San Diego Padres face off against the San Francisco Giants in MLB action on Wednesday, June 4, 2025.

The game is scheduled to be played in San Francisco.

The San Diego Padres come into the game with a 35-24 record, placing them second in the NL West. The San Francisco Giants hold a 33-28 record, good for third in the NL West.

Pitching Matchup

Right-hander Nick Pivetta is scheduled to start for the Padres. He holds a 6-2 record with a 2.74 ERA, 1.01 WHIP, and 71 strikeouts.

The Giants will counter with left-hander Kyle Harrison. His record is 1-1, with a 2.51 ERA, 0.98 WHIP, and 16 strikeouts.

The Padres are favored in this matchup with odds of -113. The Giants are listed at -106. The over/under for total runs is set at 7.

Game Context

The San Diego Padres play the San Francisco Giants after Manny Machado had four hits on Tuesday in a 3-2 win over the Giants.

Team Insights

San Francisco is 33-28 overall and 17-11 in home games. The Giants are 20-4 in games when they have more hits than their opponents.

San Diego has a 15-14 record on the road and a 35-24 record overall. The Padres have a 10-1 record in games when they hit two or more home runs.

Head-to-Head

The matchup Wednesday is the fifth meeting between these teams this season. The Padres hold a 4-0 advantage in the season series.

Key Players

Jung Hoo Lee has 14 doubles, two triples and six home runs for the Giants. Matt Chapman is 11 for 34 with three doubles, a home run and an RBI over the last 10 games.

Manny Machado has 17 doubles, seven home runs and 29 RBI while hitting .315 for the Padres. Jackson Merrill is 11 for 38 with four doubles and a home run over the last 10 games.

Last 10 Game Performance

Giants: 3-7, .205 batting average, 1.76 ERA, outscored by six runs

Padres: 7-3, .216 batting average, 3.77 ERA, outscored by three runs

Injury Report

Giants injuries: LaMonte Wade (day-to-day, hand), Jordan Hicks (15-Day IL, toe), Justin Verlander (15-Day IL, pectoral), Tom Murphy (60-Day IL, back).

Padres injuries: Michael King (15-Day IL, shoulder), Jason Heyward (10-Day IL, oblique), Mason McCoy (10-Day IL, finger), Bryan Hoeing (60-Day IL, shoulder), Logan Gillaspie (15-Day IL, oblique ), Jhony Brito (60-Day IL, forearm), Yu Darvish (15-Day IL, elbow), Joe Musgrove (60-Day IL, elbow).

In summary

The San Diego Padres (35-24) face the San Francisco Giants (33-28) on June 4, 2025, in San Francisco. The Padres, second in the NL West, lead the season series against the third-place Giants 4-0. San Diego sends Nick Pivetta (6-2, 2.74 ERA) to the mound, while San Francisco counters with Kyle Harrison (1-1, 2.51 ERA). Key players include Manny Machado for the Padres and Jung Hoo Lee for the Giants. In their last 10 games, the Padres are 7-3, while the Giants are 3-7. Injuries are notable for both teams. Betting odds favor the Padres slightly, with an over/under of 7 runs.


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