Shohei Ohtani, Dodgers Face Diamondbacks in Key NL West Matchup: Game Preview & Odds for September 23, 2025

Tuesday, September 23rd, 2025

Los Angeles Dodgers Take On Arizona Diamondbacks to Open Three-Game Series

The Los Angeles Dodgers (88-68, first in the NL West) travel to face the Arizona Diamondbacks (79-77, third in the NL West) at Chase Field for an exciting matchup on Tuesday night. With both teams pushing toward the end of the regular season, the stakes are high as the Dodgers aim to maintain their division lead, while the Diamondbacks fight for position.

Pitching Probables

The Dodgers will send Shohei Ohtani (1-1, 3.29 ERA, 1.07 WHIP, 54 strikeouts) to the mound. The Diamondbacks counter with Brandon Pfaadt (13-8, 5.02 ERA, 1.34 WHIP, 138 strikeouts). This pitching duel should set the tone for the series opener, with plenty of eyes on Ohtani as he looks to add to his impressive strikeout total and Pfaadt striving for his 14th win of the year.

Weather

Today at Chase Field, expect clear skies with temperatures around 87°F at game time. There is no chance of precipitation, and winds will be light at 5 mph. These ideal conditions should make for a perfect evening of baseball.

Team Snapshots

Arizona holds a 79-77 overall record and has been strong at home, going 42-36 at Chase Field. The Diamondbacks’ hitters have posted a .325 on-base percentage, ranking them seventh in Major League Baseball.

Los Angeles enters with an 88-68 overall record and a slightly below .500 road split (36-39). Dodgers slugging is a major team strength, with a .440 slugging percentage, good for second-best in the majors.

This game marks the 11th meeting between these division rivals in 2025, with the season series tied at 5-5.

Top Performers

For the Diamondbacks, Geraldo Perdomo has starred with 31 doubles, five triples, and 19 home runs while batting .290. Gabriel Moreno has heated up, going 14-for-38 with a double and two home runs over his last 10 games.

On the Dodgers’ side, Ohtani leads with 85 extra base hits (24 doubles, eight triples, and 53 home runs). Michael Conforto is in strong form as well, collecting 12 hits, two home runs, and seven RBI over his last 10 games.

Latest Trends and Records

Over their last 10 games, the Diamondbacks are 7-3 with a .284 batting average, a 3.71 ERA, and have outscored opponents by 12 runs. The Dodgers are 6-4 in their last 10, hitting .274 as a team with a 3.85 ERA, also outscoring their opponents by 15 runs in that span.

Key Injuries

Diamondbacks notable injuries: Tyler Locklear (10-Day IL, elbow), Pavin Smith (60-Day IL, quadricep), Lourdes Gurriel Jr. (10-Day IL, ACL), Kevin Ginkel (60-Day IL, shoulder), Tommy Henry (60-Day IL, elbow), Christian Montes De Oca (60-Day IL, elbow), Justin Martinez (60-Day IL, elbow), Cristian Mena (60-Day IL, shoulder), Corbin Burnes (60-Day IL, elbow), A.J. Puk (60-Day IL, elbow), Blake Walston (60-Day IL, elbow).

Dodgers notable injuries: Michael Kopech (15-Day IL, knee), Will Smith (10-Day IL, hand), Brock Stewart (15-Day IL, shoulder), Roki Sasaki (60-Day IL, shoulder), Tony Gonsolin (60-Day IL, elbow), Evan Phillips (60-Day IL, forearm), Kyle Hurt (60-Day IL, elbow), Michael Grove (60-Day IL, shoulder), Brusdar Graterol (60-Day IL, shoulder), River Ryan (60-Day IL, elbow), Gavin Stone (60-Day IL, shoulder).

In Summary

The Los Angeles Dodgers look to maintain their NL West lead as they open a key series against the Arizona Diamondbacks, who are battling in the thick of the division race. With strong pitching matchups, in-form hitters, and ideal weather at Chase Field, this contest promises to be a pivotal game for both squads as the 2025 MLB season nears its conclusion.

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